J. Victor Small, Klemens Rottner (auth.), Marie-France's Actin-based Motility: Cellular, Molecular and Physical PDF

By J. Victor Small, Klemens Rottner (auth.), Marie-France Carlier (eds.)

ISBN-10: 9048193001

ISBN-13: 9789048193004

This publication offers the mobile, molecular and actual points of strength and circulation via the self-assembly of actin, essentially the most ample proteins present in cells, into cytoskeletal filaments. « Actin-based motile strategies » are liable for a wide number of motile actions equivalent to chemotactic locomotion, embryonic and metastatic telephone migration, wound therapeutic, eukaryotic cytokinesis and bacterial plasmid segregation, endocytic and phagocytic actions, in addition to morphogenetic techniques together with, axis patterning in early embryos, axonal development in mind improvement, and the immune reaction and synaptic plasticity strategies on the starting place of studying and reminiscence. The booklet describes how the lately undertaken multidisciplinary and multiscale ways have explored the molecular and actual mechanisms on the foundation of strength and stream produced through actin self-assembly. the selected themes convey how advances were made within the box of mobilephone motility end result of the development in dwell mobilephone imaging, gentle microscopy, more advantageous answer within the constitution of huge protein assemblies, the biochemical research and mathematical modeling of actin meeting dynamics and the improvement of nanotechnologies allowing us to degree forces within the variety of pico- to nano-newtons produced via actin assemblies.

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Extra info for Actin-based Motility: Cellular, Molecular and Physical Aspects

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Brakebusch. 2005. Cdc42 is not essential for filopodium formation, directed migration, cell polarization, and mitosis in fibroblastoid cells. Mol Biol Cell. 16:4473–84. , K. Wennerberg, and K. Burridge. 2003. Integrin signaling to the actin cytoskeleton. Curr Opin Cell Biol. 15:572–82. V. M. Mebane, U. Philippar, M. A. Rubinson, S. E. Van Veen, C. Furman, J. S. Alberts, S. B. Gertler. 2007. Filopodia are required for cortical neurite initiation. Nat Cell Biol. 9:1347–59. S. Izzard. 1987. Evidence for an actin-containing cytoplasmic precursor of the focal contact and the timing of incorporation of vinculin at the focal contact.

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Actin-based Motility: Cellular, Molecular and Physical Aspects by J. Victor Small, Klemens Rottner (auth.), Marie-France Carlier (eds.)

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